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Volume 37 , Issue 5
September/October 2017
Pages 705–711

Using MicroCT to Assess Periodontal Regeneration Outcomes—Comparison of Image-Based and Histologic Results: A Case Report

Alberto Rebaudi, MD, DDS/Paolo Trisi, DDS, PhD/Giorgio Pagni, DDS, MS/Hom-Lay Wang, DDS, MSD, PhD

PMID: 28817135
DOI: 10.11607/prd.2816

The purpose of this study was to compare microcomputed tomography (microCT) and histologic analysis outcomes of a periodontal regeneration of a human defect treated with a polylactic- and polyglycolic-acid copolymer. At 11 months following the grafting procedure, the root with the surrounding periodontal tissues was removed and analyzed using microCT and histologic techniques. The results suggest that microCT three-dimensional analysis may be used in synergy with two-dimensional histologic sections to provide additional information for studying the regeneration outcomes normally reported by histologic biopsies in humans. Additional data is needed to validate these findings.

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